ORIGINAL: Fl Still HunterI am mostly a high power rifle reloader and usually load magnum cal's to the max, if the accuracy is there. Florida Still Hunter !!
The key is bolded above. Many people have found that the 150-grain Pyrodex load leaves something to be desired accuracy-wise. By all means, use the most accurate load your gun can handle - if this load is 150 grains, and gives you higher velocities and flatter trajectories, so much the better.
One of my most accurate loads in my slow-twist .50 is 140 grains of loose FFFg GOEX ClearShot BP substitute powder with a 370-grain Maxi-ball. It averages 1750FPS MV. Unfortunately, Maxi balls have a very poor ballistic coefficient, so the trajectory is not flattened much at longer ranges. I use it because it is very accurate.