The range for a short barreled Revolver will depend on shooter skill level. I shot one Buck at 100 yards with the 300 grain but that was with a scoped Contender. I shot a Mule deer with my S&W 5 inch revolver and the 300 grain Hornady at about 70 yards. With a short barrel and iron sights, that would be about as far as I would try. You should have about 800-1000 pounds of ME at 100 yards. I had one 300 Grain Hornady pass through a Mule deer including the off shoulder at 200 yards but that was from a 44 Mag rifle. So the round is good to about any distance that you can connect with the deer.