I have a pedersoli sharps replica. I shoot the standard lead 300 grain remingtons. They kick my ass from the stock end of the rifle so I have no doubt they would do the same from the muzzle end to anything you can hit with it. I would not hesitate to shoot ANYTHING ON THE NORTH AMERICAN CONTINENT with this bullet. But I believ 150 yards is the absolute limit. I don't shoot mine at more than 100 yards.
okcmco
PS this load is deadly on hogs