Greener: I shot a nice big 8 pointer 2 years ago in PA in the regular big game season.
I did use the QT'S 45 in 350 grain 54 cal, shot was 75 yards ,the buck was hit high in the lung area : the buck did 180 turn and went up the ridge.I had the same problem no exit hole and tracking was a nightmare.I did find the 8 pointer he had only one hole were the bullet when in,turn the lungs to jelly field dress to 187 lbs.I was using 85 grains of triple 777 powder.
I had great sucess with precision silver lighting in 300 grainers ,early in the season I took a nice doe about the same yardage ,man what a difference a bullet makes .The doe took three steps and was down,A exit hole the size of a 1/2 dollar exit hole ,a blind man could follow that blood trail
I just switch bullets to a 375 grain buffalo SSB and 85 grains of goex 3f .I will see if I I use my inline this year how the bullet works
I have my flinters ready to go.