I have shot a lot of deer with the 308 but never any with a factory load. I load the 150 Grain Sierra Pro-Hunter in my 308. The Federal Blue Box ammo should work very well and is pretty cheap. I thing they load some with the Speer 150 grain Grand Slam. I have used these in my 06 with good results. I juust checked with Midway USA they have the Federal loaded with Grand Slams on sale for 7.85 a box. Those are good shells at a good price.