The .25-06 for pronghorn, deer, sheep, caribou.

If you were hunting Elk, Moose, Grizzly Bear, and Brown Bear I would go heavier than the 7 mm Mag -- perhaps a .338 Winchester Magnum. I would use this same cartridge on Goat. Thus, I don't see what niche of big game hunting where the 7 mm Mag bests the .25-06.

But this is just my opinion, and I acknowledge that I am not an objective judge of this issue -- I have a .25-06 and I love it!!!