RE: 25-06'?
I have a Tikka in 25-06. Great caliber. There isn't anything that a 270 will do to a deer that a 25-06 won't except kick you a little harder when you shoot him. The 25-06 shoots very flat, recoil is mild and it puts the hardsmack down on deer sized animals.
The 270 is certainly much more popular but it's been around a lot longer and unlike the 25-06 had a very famous gun writer to champion it's virtues. But I can tell you this, everyone I know thathas taken the road less traveled and boughta 25-06 for a deer rifle never goes back to anything else.