Don't know where you will be hunting or your range limitations. But if your shots would be less than 100 yds. you have tons of options. What actions do you like. I would tell you to get something that delivers a minimum of 1200 ftlb of energy at your maximum range.
If your limited to commercial ammo or on a tight budget, you can't go wrong with the good old .30-06 and you can usually pick a good used one up at just about any gun shop.