I have never killed anything with 243 ballistic silvertips, but 270 and 300 WSM have performed flawlessly for me. My son and I have killed a total of 15 deer and NUMEROUS hogs and coyoteswith them and not one has taken a step. Every bullet has completely passed through whether shoulder or neck shots. We have killed at ranges from 30 yards to 300 yards with the same results. I havesighted in my 243 with ballistic silvertips and have had great range results out to 250 yards. I personally would not be afraid to hunt with them.