Well, I'll throw a bit of a curveball here. I just got back from Pagosa Springs CO with elk meat in the cooler. I used an Encore 209 in 50 caliber with 140 grains of Triple seven and 348 grain Powerbelt Aerotips. One shot at about 75 yards, my cow took two steps and tipped over. The cow was walking directly at me and I put the Powerbelt into her chest. There was an exit wound and massive amounts of blood to track if I would have had to go more than the two steps she took.
I'd use this load again for elk and hopefully I'll get a chance again next year.

Bill the Dog