I use my .270 all the time for yotes, and it works great. The wind if a HUGE factor as some of the guys already said. In KS it is open all year long. I usually find it best during the winter in the early mornings using a squealing rodent call, also have used a pup in distress tape, both work well but the rodent call will be more successful for longer periods than the other.
Squirrel Master...i agree with you, hunting them with a 20 gauge is a BLAST, but i wouldn't suggest it to a guy going out on his first yote hunt, keep with you rifle untill you get the hang of it and how they yotes work and watch how they they respond to different calls and everything else, always keep your eyes open, and when usuing a rodent call watch out for mt. lions and cougars depending where you're at. These will also come in just as fast as anything to this call. Hope something in there helps you out a bit, and good luck, let us know how your first hunt turns out!

***SHOOT FIRST ASK QUESTIONS LATER***
--Jason