RE: 50 cal. or 45acp
ah you must be young or fairly new too muzzleloading? 15-20 years ago when Sabots began taking over in muzzleloading, the only bullets available WERE pistol bullets. Xbullets, SSTs, Powerbelts etc... none of those were around back then. The XTPs are still used by ALOT of hunters today. They perform well when not driven over 2k fps.
The only thing you have to be careful of is remembering that you will possibly be driving them much faster with your ML than they were designed to work. A hollowpoint designed to open at 45ACP and LC velocities will more than likely overexpand and not penetrate well when fired into game at ML velocities. For practice and plinkin, most any of them would be fine. Just stick with quality ones like XTPs, CorBons etc when actually using them to take game with.
Good luck,
RA