Different sabots are made for each caliber depending on the projectile you want to shoot. A common .50 caliber sabot will shoot the .429-.430 (.44 caliber), .451-.452 (.45 caliber)and .457-.458 (.45 caliber)diameter bullets. In the .45 caliber rifle the sabots are aimed at the .40 and .357 caliber bullets from what I have seen. I personally do not shoot a .45 caliber.