I have the common Tru-Glo 3 pin sights on my lefty bow. When I started out, I kept them short at 10/20/30. I stayed at 10 yards for months, while I learned to shoot properly. Then moved on from there.

Currently, I have the 3 pins set at 20, 30 and 40 and leave them set at that. For a 25 yard shot, I just sight in between the 20 and 30 pins and I'm dead on.