If sabots are legal I would go that route with a Knight Disc. Something like a 250 grain Barnes Expander on top of 120 grains of powder. Or perhaps some 375 grain Buffalo Bullet SSB's on a 100 grain area load.Shockwaves would also be a good choice in the 300 grain range, although I think any of them would do the job if placed in the right spot.

If sabots are not legal then I would look at the 460 grain No Excuses Conicals. No Excuse Conicals are a slip fit, easy to load and because of their weight even 85 grains of powder is lethal to anything they come into contact with. They are very accuracte out of my Wolverine II where as powerbelts are a disappointment to say the least. Also if you use powerbelts be sure and check them from time to time to make sure they have not moves off the load. They could cause a barrel obstruction under the right circumstances.