I only have one piece of evidence that says 100grains of Pyro WILL kill elk.
My trophy and I are second row, on the right. Grossed 368" netted 364":
http://www.nmtrophyhunts.com/elk.htm
That was in 98 and was with my lil ol 22" Wolverine with 100grains of Pyro under 250grn Xbullets. At 100yds the bullets would strike 3" high but at 150 they would dive nearly 6". But I killed ALOT of deer with that exact gun and load out too as much as 175.
LOL the bull was only 30yds away, he stoodup on his hindlegs and crashed off through the timber and piled up 20yds away. The lil bullet made it through both HUGE lungs on that beast!
I had a new respect for dat lil ol Wolvie after that hunt,
RA