I just started to reload and sight in a (.44 Mag)320 gr hardcast LFNGC from Cast Performance (Cabelas) with 21to 21.5 gr of H-110, Fed Case and Fed Large Mag Pistol Primer # 155. Aim for the shoulders and hit as many bones as you can. I shoot this load out of a Ruger SRH 7 1/2" barrel.