I agree with James that both are easy to load for...I got sub MOA groups with both calibers with routine load development... I also agree that the 7mm-08 would be a better choice for game larger than deer..

However, I consider the 25-06 as better rifle for long range "beanfield" shooting for deer from stands, and the 7mm-08 as a better choice for general "take 'em as they come" deer hunting under varied conditions...The 25-06 is at it's best in a heavier long action rifle with at least a 24" barrel... Both are perfectly adequate out to 300 yards or a bit beyond...If ranges are longer than that the 25-06 has the advantage...