The .450 is above the realm of the .444,but as stated befor the .444 is no slouch either.The biggest problem the .444 was when it was introduced they loaded it with same bullets the .44 mag was loaded with.This caused the bullets to seperate or blow up,wich in turn gave the .444 a bad rap.

I like the .450 for elk and moose in close 1/4's,and would use it for grizz in a heart beat.If you load solids in it it would make a good African game gun I would supose also.

With todays bullets and ammo the .444 and the 450 can handle almost or most of N/A Biggame.
BBJ