Given that the bow is properly tuned, the energy imparted to the arrow is applied directly in line with the arrow shaft. In essence all the bow knows of the arrow is what it sees at the nock end. So the answer to your question, is no, the KE impated by the bow is a function of the total arrow weight, regardless of where that weight is distributed. If you had a way to guide it, you could conciveably shoot a 350gr bullet off of your bow string and get the same KE as well.

Now arrow flight is something different.