ive read up alot about using this on deer. on replys to this post i would apprciate it that u dont tell me im overgunned or anything of the sort. im comfortable with this cartridge and every thing about the gun. my question is ive read that meat damage with this caliber has alot to do with the type of bullet you use. my grandpas old load for this gun is sierra pro hunter 150 grain around 3200 or 3100. i live in one of those places where u can get shots at 10 yds or 300 yds. is this load goin to penetrate and not do too much damage at close shots. i will be reloading so i have the choice of bullets. thanks alot guys.