ORIGINAL: SWAMPMAN
Additionally I responded to zrexpilot who remarked about "fist sized holes" in his venison. I'm sure you can kill whitetail with a 22-250, I just don't know why you'd take a chance on wounding game when another rifle caliber can better do the job. .
Wounding ? Ha Ha ! Ive never seen a deer walking around with fist size holes in their chest . LOL
22-250 is a fine deer cartridge. Specially when deer here rarely exceed 150 lbs.But If ever I got to hunt 300lb deer up north, well then I would have to step up to my .243.

But I guess for some of you who cant shoot and need something to take down a gut shot deer quickly go for nothing less then a .300. Ha Ha. LOL.