RE: 22-250
I know several ranchers who hunt deer with their 22-250 rifles because many of them always carry one in their trucks. I have no expierence shooting deer with the 55 grain Ballistic tip but the 55 grain Hornady works well. I have seen a few big mule deer bucks taken with the 22-250 which is a legal deer gun in our state. As is the 223.
I wouldn't use one now because I have rifles that are better suited for deer hunting. However at one time the only rifle I had that was legal for deer in our state was a 222 Savage O&U rifle. It worked well for me and I never lost an animal while using it. 25 caliber is my minimum now.