If you want a dual home defense and hunting gun I would consider...

Glock 20 in 10mm. Buy an extra hunter barrel 6" for hunting.

.44mag with a 6" barrel and use .44special for home.

I agree with others that you would be better suited with two differn't guns, but sometimes money is just not there.

I know people will not like the 10mm suggestion but with the 6" barrel and shots no further then 40 yards you will kill deer just as dead as with a .41magnum with the proper load choice when using the 6" barrel.