The Lee Aniversary kit is decent for starting or if you aren't doing a million rounds at a time. The 30-06 is pretty easy to reload for, anymore factory loads are really pretty hard to beat, but you can pick and choose bullets, etc..
For deer (in my rifle), the Nosler Ballistic tip over 59.0gr of IMR4350 was super accurate and plenty fast (around 3000fps).
Deer hated that load.
For the bigger stuff bump up to a Partition or Interbond in 180gr. I've had good luck with both of those.
Just my $.02
Erik