I won't sacrifice acuracy for any cartridge. Now that needs to be qualified. I have a cooper 22-250 that will shoot 1/4 MOA groups consistantly. I've even shot zero groups with it at 100 yards. I'm confident with it on prairie dogs out to 500 yards. Now, are my hunting rifles that accurate? No, but all my weapons are sub 1 MOA guns. Thats my criteria. Its a personal criteria, and may be overkill in some peoples eyes. If any of my guns will not shoot under 2" at 200 yards off a bench I trade them.

The true test thought is shooting them with out a bench. I spend enough time shooting that my techniques are solid. I determine how far I can shoot confidently with my weapons prior to the hunt. Another factor in that determination is the position being shot the type of rest or lack there of. For example, I'm confident with my 338 win out to 350 yards if I'm prone or sitting with a rest (tree or backpack to brace against). Off hand 200 yards is the limit. So the answer to your question is: None! If a cartridge is inaccurate I won't shoot it. If a weapon has more recoil than I can shoot accurately then I pass on it. I believe in taking as much power as you can shoot well. As I get older my tolerance for recoil may subside. It may be that If I want to hunt elk I must use a smaller weapon. I'm not concerned with that because I know that a well placed shot from a number of "lighter" cartridges are sufficient to harvest an elk. I personally think that the 338 is a man among boys when we talk about elk cartridges though.