I've shot the 385 Great Plains with & without wads in my Knight USAK and accuracy results were Identical.

The rebated base of these bullets tend to negate the affect wads have when used on flat based bullets like the No Excuses 460s. I can see why Hodgdon would recommend wads when using 777 - to try to prevent this hotter powder from burning & distorting the bullet's base. But I think that when using moderate powder loads (like the 80 to 90gr loads I used), that the wads are a non-issue.

Now using those sabot sub-bases like Roskoe spoke of is an intreging idea. Those should create a nice tight pressure seal and significantly increase velocity. BUT these big bulky bullets CAN be pushed too fast - so again, the sub-bases may not be cost effective either.

BTW I recently tested some of the 385 Great Plains without the wads and they registered an average of 1343fps with 85gr of 2fg 777 - giving accuracy as good or better than what you reported. Thats 1542ft lbs of killing energy at the muzzle - which is plenty good for hunting out to 100yds.