I have a .308. I love it. I used a 110 varmint load and it knocked the yote off it's feet. But it DID make a mess. I'd say a heavy grain like 150 or 180 would do the trick. Actually you might even want to look into the 168 match round. It's accurate and not designed to expand like a hunting round. It should just pass through with 2 little holes in the pelt, one comming and one going.