It depends where I'm hunting. Around home where there are a ton of deer and not many yotes I'd probably pass. Funny thing is I rarely see yotes, It's usually the neighbors dog that's tempting me.
Up north where I hunt where the deer are fewer and the yotes are more prevelent I wouldn't hesitate. I don't eat yote but have a pelt I wear on my arm as a puppet. It's great for scaring my boys and "attacking" my cats. In fact everyone in my house like it except for my wife.

Go figure.