I have a Browning Buckmark Nickel with the 5 1/2" barrel and I really like it. A few years ago I put a Bushnell Holo sight on it and that is a neat sight. I also really like the Ruger 22/45 with the 5 1/2" barrel. The Ruger MK II are very good guns and the MK III has improved features.
I personally like the Ruger and Browning .22s the best, but you should go handle some and see which one fits your hand the best.
Good luck.