I don't shoot a Pursuit, but I'm a big fan of the Fusion 300 Grain Bullets as well as the 300 Grain Speer Deep Curls with a Harvester black sabot. I shoot these with either 100 grains of loose Pyrodex or 2 50 grain pellets. They shoot well at 100 yards in everything I've tried them in.
I want to try Blackhorn 209, but I haven't yet.