A couple of variables i'd need to ask 1st:
1) are you an experienced hunter
2) do you handload
3) yardage that youre gonna shoot deer at
Reason for these questions are ive seen some nice deer taken with the 223 with handloaded NP and Barnes TTXS.
These guys where experienced hunters.
If you put a quality bullet thru a deer vitals with a 223 and keep the yardage reasonable its gonna kill them.
HOWEVER... if it was me, out of the 3 cartridges you mentioned ,I'd pick the 308 and shoot plain ole C&C factory fodder in 150g class... because IME that's what has killed deer for me!

Of those 3 to be used in WI I'd FOR SURE recommend the 308. Sure I love my 22-250 & I've killed a doe with it at 300yds before (neck shot). But you are in WI & can very likely get a crack at a 300#+ deer, I would NOT recommend anything smaller than a 243 for such critters. (& even with a 243 you better have QUALITY bullets shot ONLY at ideal angles & even then it might not reach all the way thru a brute buck!)

A 308 with 150-165 bonded "super bullets" or even better, my fav the Barnes, will drill thru the biggest whitetail around! Distance & power wise the 308 can kill well in excess of a 1/2 mile but I'd personally keep the shots under 500yds...

.243 worked fine for me this year! Nice buck 80 yrds to 100 yrds. No problems. Just gotta know your range and limits thereof.

I prefer a 3006 and have killed many deer with mine Ive shot deer out to 300 yards but I prefer shots of 100 yards or less I shoot a 150 grain round and have very good results

Of those 3, the 308 wins hands down.

.308 hands down out of those choices!

+1

At first I thought it was a IQ test - LOL !!! :lmao:

Oh, DEAR GOD.
Are we really gonna do this again?

OP, use the search option at the top of the page.

Every couple of weeks, this same or nearly same thread pops up.

At least this time the guy is actually asking for advise instead of bragging about how good he is on big game with his .22 caliber cartridges:confused0024:

That's true.
I doubt it won't devolve into that though. They always seem to.