I've bow hunted for a long time. Even before compound bows. Back then a 25 yard shot was a long one. Today with as you say the fast speed bows longer shots are possible and practical provided you as the shooter are capable 100% of the time. And many on here are probably speaking of whitetails in the woods or over a food plot. If you bow hunted out west for mulies, elk, or pronghorn you will get much longer shots than 25 yards. I practice out to 70 yards and I would not hesitate to take a 50 yard shot at an animal (60 yards on an elk or moose) if conditions were perfect. That being said, my longest shot on a whitetail was 43 yards but every other one has been 25 yards or less. I try to set up so my farthest shot is 30 yards.

Been stated already

Reaction time will change also. The sound of the bow will take longer to reach the deer.

Let's both recognize that this entire discussion is assuming that the deer's unabashed reaction is to get the he11 out of dodge, rather than simply LOOK for the origin of the sound. It has never been my experience in killing deer with a bow that they immediately bolt on the shot unless the shooter took a foolish shot with an alerted deer looking right at them.

More importantly for this discussion, you've wholly neglected the travel time of sound. Unless the shooter is very stupid, they don't shoot a deer looking at them, so the only stimulus that they'll receive is the sound of the shot.

(I'll enter into argument here, without discussion, that having listened to modern bows at range to see how much sound they put off, at 40-60yrds, the sound of the shot is quite low, definitely not enough to cause instant flight for most deer - as has been my experience in shooting a deer out of groups in the field).

You cannot neglect the sound transfer time in this, as it's a substantial contributor to the overall reaction time and movement time of the deer.

60yrds = 164milliseconds for the sound of your string to reach the deer
300milliseconds to start moving AFTER HEARING THE SHOT
464milliseconds before the deer STARTS moving

Flight time is 600milliseconds

136milliseconds using a 1G drop = 3.35"
Using a 2 1/4" cut on a 6"x10" vital, that's plenty of margin for error.

Shooter accuracy tends to be a much more relevant contributing factor than "string jump". Way too many guys blame $hitty shooting on "string jump" as it hasn't been my experience that deer BLITZ OUT OF TOWN as soon as they hear a bow shot.

absolutely nothing wrong with a longer shot 50,60 or even 70 yards as long you practice religiously and are proficient with your equipment and the deer is relaxed and not alert..

I choose to limit myself to 50 yds beyond that as stated before I don't practice.. I do shoot every day at least 15 to 20 shots.

I practice out to 70 yards as that is all my 5 pin sight is set for. Those who are not capable of making longer shots on deer should not try to enforce their limited capabilities on those who can and have made these shots.

You're hesitancy makes me think zero. Is it zero?

I've never taken a shot at a deer over 20 yards.. Yet I've never had a chance or a time where I've needed to. Just because I can shoot a deer at 60 yards doesn't mean I need to. I have two bows one I won't shoot over 30 yards with because I am not confident with it and I know it's too slow.. My other bow however is fair game.

So you have zero real world experience with shots at a live animal at fifty or more yards. That's all I needed to know.

if I was shooting a Mathews I wouldn't shoot beyond 30yds either ..lol

Just ribbing you....