It depends on where i hunt.
in the pastures long shot say 250 to 400 yards.i use my 7mm stw ,300 win mag or 25-06.

open timber ,pine fields. i use my 270,30-06, 6mm rem or 243.

thicker timber, bottoms. i use my 308, 30-06,or 44 mag.
well heck sometimes i just use whatevers on my mind before i go. i have been known to go to my stand with a 357 mag or a 41 mag. shotgun or bow or crossbow. i dont have a spear yet though. i just cant answer this question.
aint america great!