Excellent summation, Cougar Mag!

What great benefit is gained by possibly putting the setup on the edge of reliable and forgiving performance and durability by trying to increase the KE and momentum beyond what the appropriate setup naturally and best provides, and what is generally necessary? In the end, regardless of all of the computations, for most bowhunters it will still boil down to a common and long-established requirement; the shaft must be correctly matched to the specs of the bow and shooter.

Any compound that has a draw-weight suitable for hunting (specific) large game will do the job as long as the arrow is appropriately matched to the particular bow and shooter. Most "spine" guides will indicate the correct shaft(s) to use without having to engage in a lot of physics and math. From that point, you simply tweak the bow and arrow until flight and accuracy is good.

If your gear is tuned properly and your shooting skills are fitting, a shaft through both lungs will put the deer down, regardless of not getting full penetration and a blood trail

In the end, a scientific application of KE/momentum is an individual thing and does no harm unless the performance of the bow and arrow is adversely affected.