Not a problem.

More than a few years ago, when CCI began to manufacture rifle primers for reloading, I bought a thousand to try. They were natural brass--as opposed to Rem and Win who used plated brass. The CCI's were several different shades. I was curious about any differences in accuracy, but could find none. Apparently when the cups are stamped from brass sheet, there is some discoloration which is noticeable in the finished product.

Today, both Rem and Win are using unplated brass for their primers (plating adds to the materials cost) and it is not unusual to find several different shades of primers in a box.