“Mathematically,” if your scope is parallax free, a slug gun will never notice the difference between two shooters. Even a precision rifle will have less shift between two shooters going right to left handed in the same relative position than it will for a single shooter going prone versus free recoil.
I shoot both right and left handed quite often, hand my rifle to my left handed sis, or my wife 6” shorter than I or my son 2 full feet shorter than I, or any of a few dozen long range rifle students I’ve taught/coached over the years, and with parallax free optics, any will shoot sub-MOA out to 600 yards, or beyond.
That’s not to say two different people won’t jerk triggers differently, such if the rifle is zeroed to accommodate the first shooter’s bad habit, the second shooter’s bad habit won’t pull the bullet into zero in the same way. But the theory of “different shooters = different POI” is dramatically overhyped.