Over half of our members on lease shoot 270W - It just plain kills deer.
Our unwritten rule is that if a yote or hog shows up - shoot'em, deer hunt is over.
270W just plain kills yotes and hogs, too.
Here's a ballistic comparison:
270W w/ 150gr at 2850fps MV is 2704ft-lbs ME.
270W w/ 130gr at 3060fps MV is 2702ft-lbs ME.
6.5CM w/ 140gr at 2710fps MV is 2283ft-lbs ME.
6.5CM w/ 125gr at 2850fps MV is 2254ft-lbs ME.
The 6.5CM should work OK, too.
Just not anything special like its advertised.