I believe your bow is designed to shoot best at peak weight. So say a 70# can be adjusted from 60-70#, it's designed to shoot best at 70#.
I personally adjust limbs evenly, say 2 twists up top, 4 below, 2 more up top, pattern, but that's just me.
Regardless I'd at least match top and bottom, like 4 top, 4 bottom.