30.06 with 180 gr bullet will take care of all that. Get a 12 twist barrel. I like the Douglas 5A contour that will give you a medium weight barrel that you can set back several times if you start off with a 26" barrel. If you are planning on shooting a long time you might consider having a custom reamer made that way all your 30.06 fired cases should be interchangeable since they would be cut with same reamer.