If your wheel gun is in time you won't have that problem (well, serious problem as ALL wheel guns have a little scrape off when jumping from chamber to barrel) unless you have some "tilt" in your loads. I used to shoot .38sp out of my .357 Colt Python all the time for practice (still kicking myself in the butt for selling that damn pistol) and the only time I ever had serious scraping was when I didn't seat the bullet dead straight. I don't practice a whole heck of a lot with my current .357 since I don't hunt with it all that often and the only loads in .38sp I load currently are for my wife's little Lady Smith.