I killed my first Deer, A 10 point, with a single shot .223
It killed him, dropped in his tracks. But it is not something I would suggest. I was real little was why I used it.
It turns out the bullet hit him in the shoulder & broke in two.
1 half stuck in the shoulder, the other broke through a Rib, punctured a lung, And lodged in his spine. Otherwise there might have been a different outcome.