I have shot Buffalo Bore through my Ruger Blackhawk in .45 colt. There is noting I am going to hunt that needs that kind of power, certainly not deer. The recoil is excessive and I am not recoil shy, it just beats you up and your gun as well. It would actually cause the cylinder pin to come out a bit. I put in a heavier spring to stop that but do not use Buffalo Bore any more. I switched to Hornady leverevolution and it has all the power I need.