Normally not. Generally the ammo companies are going to want to use a faster powder to save a little money. Less powder in millions of bullets every year will add up. By the way black powder doesn't have to be compressed in a bullet either. Traditionally they were, to get the optimum power out of a cartridge. Say a 45-70 would have 70 grains of powder and it would be compressed. But you could load a 45-90 with 70 gr of powder and it would be safe. Not talking muzzle loaders here, just bullets. You absolutely have to compress the powder with the projectile in a muzzle loader.