my father has both an older single six and a new heritage arms 22/22 mag combo. I would recommend the steel frame heritage it's a little more but I feel it's the best choice. price around $250-290. gandermountain has the 22 only with aluminium alloy frame for $199. also you can get extra cylinders for the heritage off their webpage and grips.
http://www.heritagemfg.com/index.cfm