I got the same shot last year at my buck. All I saw was a white tale and two horns. I aimed right between the two horns about six inches below. He didn't even flinch I I didn't ruin one scrape of meat. If you actually shoot it in the body from behind you can kiss most of the meat goodbye.
Just to be clear obviously I saw the deer before it offered this shot and wasn't shooting blindly at a white tail with horns... and he was blowing at me when I pulled the trigger.