When I got my first muzzleloader I used what the salesman recommended, a 295 grain hollow point powerbelt and 2 50 grain triple 7 pellets. I practiced with that load for a few months before season and it shot really well.
About 2 hours into black powder season I shot a really nice doe at 85 yards. The powerbelt disintegrated upon hitting the rib cage. Luckily a few pieces hit the vitals and I found her about 75 yards away. After that I found the forums and found some bullets I like better. I think if I were to use a powerbelt now I would use the heaviest one I could get and reduce the charge.