I use the 45-225gr FTX on targets and they start to expand just passing through a single layer of cardboard. I used a box one day to confirm my earlier results. I could see fragments hitting the back side of the box after the 45-225gr hit ONLY some card board. The second main hole in the box was also VERY large compared to any other bullet i shot through the same thin box.

They are super accurate for me even in my smokeless MLs but there is no way i would use them on anything bigger than a coyote if you push them over 1600fps.

If you want to shoot a light weight, try the Barnes 45LC-225gr XPB. They are absolutely deadly out to 150yards and you can push them as fast as you want. I shoot them well over 2300fps in a smokeless ML. They are devastating on deer size game and my media tests. Even if you could blow off all the copper petal, the base will still weight nearly 200grs. I know for sure because ive done it.

I also use the 458-325gr FTX and its awesome over a very wide range of velocity. You can push them as low as 1600fps with no worries about enough expansion on a typical distance. Longer range may require a bit more MV for best expansion. Ive pushed them into the 2300fps range and the performance is amazing considering the cost. They are the rage for many smokeless owners because they perform so well over a huge fps range and a pass through is very likely.