1) What feels best in YOUR hands?
2) Which will carry better, if you'll ever carry it? (Most cheap out on holsters so consider weight)
3) Do you need double action?
4) Grips are moot in the initial decision, since they're easily changed at little expense.
Now if you know you're going towards the hot 45lc loads anyways, why not simply buy a .454? Buy what suits the needs not what will make do. As for strength comparisons, the RH and SRH use the same cylinders so that aspect wouldn't matter. After all, it's the cylinder that holds all that pressure in.
Personally, the RH models are too large and lack the class and style of a fine SA.
