i agree with 7mmxbolt, stay away from the shoulder shot if all possible. quiet a few guys here use the 243 win with 70gr nosler btip, 44 grs of varget. very devastating on deer. if a bullet passes through, you loose shocking power. the 70gr btip stays in the animal, deer absorbs all of the energy. we use the 243wssm case with the btip 70grainers. neck shot, neck shot, neck shot. hit 'em in the base of the neck. they can't die any faster. no trailing. small hole in, NO HOLE OUT. we killed everything from does to several 300lbs 200"+ bucks with it. from 7yrds to 311yrds. pics with proof, just my opinion.